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- Ondet Syrup is used to prevent nausea and vomiting related to highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m2. This medicine works by blocking the release of serotonin which may stimulate the vagal afferents through the 5-HT3 receptors and begin the vomiting reflex.
- Ondet is also used to prevent nausea and vomiting related with initial and repeat courses of adequate emetogenic cancer chemotherapy, to prevent nausea and vomiting related with high doses of radiation ( radiotherapy ) in patients having either total body exposure to radiation (irradiation), single high-dose fraction to the stomach, or daily fractions to the stomach, and to prevent nausea or vomiting occurring after a surgical operation (postoperative nausea and/or vomiting).
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