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- Ribociclib is used to treat breast cancer in women after menopause. It works by slowing or stopping the growth of cancer cells.
Indicated as initial endocrine-based therapy for the treatment of postmenopausal women with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)negative advanced or metastatic breast cancer
Ribociclib (initial dose): 600 mg PO qDay for 21 consecutive days followed by 7 days off treatment resulting in a 28-day cycle
Letrozole: 2.5 mg PO qDay taken through the 28-day cycle