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Azadirachtin buy in Theni Allinagaram
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Azadirachtin

Azadirachtin

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The acute oral toxicity in rats fed technical grade azadirachtin ranged from greater than 3,540 mg/kg to greater than 5,000 mg/kg, the highest dose tested when administered
undiluted to albino rats (1, 2, 3).

The acute inhalation toxicity study in rats exposed to technical azadirachtin showed that the acute inhalation LD50 is greater than 2.41 mg/L per animal, the highest dose tested.
Although this figure is below the 5.0 mg/L limit test dose for an acute inhalation study, the reported concentration was the maximum dose possible under the test conditions. No
deaths occurred during the course of the study. Azadirachtin was given a toxicity classification of Category III (3).

A primary eye irritation study in rabbits exposed to technical azadirachtin was rated mild to moderately irritating after instillation of 0.1 gm of the undiluted material. At one hour post-instillation, the maximum eye irritation score was 15.3/110; by 24, 48,
and 72 hours the scores were 6.2/110, 0.3/110, and 0/110, respectively. It was given a toxicity category of III (3).

Primary dermal irritation in rabbits when tested at a single dose (0.5 gm) by applying it to the shaved backs of rabbits, did not cause any dermal irritation after 4 hours of exposure. The dermal score was zero for all treated rabbits at all examination times.
A toxicity category of IV, mild to slightly irritating,was assigned.

An acute dermal toxicity study of rabbits exposed to technical azadirachtin was performed. The material was applied for 24 hours at a single dose of 2.0 gm/kg to the shaved backs of the rabbits, that caused dermal irritation which resolved by day nine.
Azadirachtin was classified as a mild irritant (3). Another study reported the dermal LD50 for rabbits to be >2,000 mg/kg (1,2).

Dermal sensitization in guinea pigs found the technical end-use product to be categorized as a mild sensitizer when administered undiluted to albino guinea pigs. The test material was considered a weak dermal sensitizer to albino guinea pigs (3).

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